Gossypol, 98+%

Product Code. 15455939

Brand: Thermo Scientific Alfa Aesar J63767.MC

Description

Lipophilic agent derived from cottonseed | CAS: 303-45-7 | C30H30O8 | 518.56 g/mol

Gossypol acts as an inhibitor for several dehydrogenase enzymes. Gossypol has also long been known to possess antimalarial properties. Gossypol provided reliable contraception. gossypol provokes infertility and causes spermatogenesis. Gossypol is used as an active antifertility agent in a variety of male animals, including mice, rats, hamsters, monkeys, rabbits, and bulls.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Gossypol acts as an inhibitor for several dehydrogenase enzymes. Gossypol has also long been known to possess antimalarial properties. Gossypol provided reliable contraception. gossypol provokes infertility and causes spermatogenesis. Gossypol is used as an active antifertility agent in a variety of male animals, including mice, rats, hamsters, monkeys, rabbits, and bulls.

Solubility
Soluble in 100%ethanol (25 mg/ml), DMF (25 mg/ml), acetone, DMSO (25 mM), methanol (2 mg/ml), ether, chloroform, sodium carbonate, and dilute aqueous solutions of ammonia . Insoluble in water. Gossypol is a male antifertility agent with antispermatogenic activity and has been shown to contain antitumor, anitviral, and antioxidant properties.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

Specifications

Chemical Identifiers

• CAS: 303-45-7
• Molecular Formula: C30H30O8
• Molecular Weight (g/mol): 518.56
• MDL Number: MFCD00017352
• InChI Key: QBKSWRVVCFFDOT-UHFFFAOYSA-N
• Synonym: gossypol, --gossypol, +-gossypol, pogosin, tash 1, racemic-gossypol, r---gossypol, r-gossypol, +--gossypol, +/--gossypol
• PubChem CID: 3503
• ChEBI: CHEBI:28584
• SMILES: CC(C)C1=C(O)C(O)=C(C=O)C2=C(O)C(=C(C)C=C12)C1=C(O)C2=C(C=O)C(O)=C(O)C(C(C)C)=C2C=C1C

• Color: Yellow to Brown
• Quantity: 100 mg
• Merck Index: 14,4528
• Solubility Information: Soluble in 100%ethanol (25mg/ml),DMF (25mg/ml),acetone,DMSO (25 mM),methanol (2mg/ml),ether,chloroform,sodium carbonate,and dilute aqueous solutions of ammonia . Insoluble in water. Gossypol is a male antifertility agent with antispermatogenic activity and has been shown to contain antitumor,anitviral,and antioxidant properties.
• IUPAC Name: 7-(8-formyl-1,6,7-trihydroxy-3-methyl-5-propan-2-ylnaphthalen-2-yl)-2,3,8-trihydroxy-6-methyl-4-propan-2-ylnaphthalene-1-carbaldehyde
• Formula Weight: 518.56
• Percent Purity: ≥98%
• Physical Form: Powder
• Chemical Name or Material: Gossypol

Safety and Handling

Product Identifier

• Gossypol

Signal Word

• Warning

Hazard Category

• Acute toxicity Category 4
• Germ cell mutagenicity Category 2
• Reproductive toxicity Category 2

Hazard Statement

• H302-Harmful if swallowed.
• H341-Suspected of causing genetic defects.
• H361-Suspected of damaging fertility or the unborn child.

Precautionary Statement

• P201-Obtain special instructions before use.
• P264-Wash face, hands and anyexposed skin thoroughly after handling.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P312-Call a POISON CENTER/doctor/if you feel unwell.

Supplemental information

• MIXTURE LIST-Contains : Gossypol

SDS

RUO – Research Use Only