PC, Goat, Polyclonal Antibody, Abnova™

Goat polyclonal antibody raised against synthetic peptide of PC.

Brand:  Abnova PAB7443.100ug

Product Code. 16070518

Description

This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq]

Sequence: C-KFKEVKKAYVEANQ

Specifications

• Antigen: PC
• Classification: Polyclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:16000) Western Blot (0.03-0.1 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: PC
• Gene Symbols: PC
• Immunogen: A synthetic peptide corresponding to human PC.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: All reported variants (NP_000911.2, NP_0010.35806.1, NP_071504.2) represent identical protein.
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: ELISA, Western Blot
• Concentration: 0.5 mg/mL
• Description: Goat polyclonal antibody raised against synthetic peptide of PC.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene Alias: PCB
• Host Species: Goat
• Purification Method: Antigen affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 5091
• Target Species: Human
• Form: Liquid

For Research Use Only