GNB3 Goat anti-Human, Polyclonal Antibody, Abnova™

Goat polyclonal antibody raised against synthetic peptide of GNB3.

Brand:  Abnova PAB18952.100ug

Product Code. 16023547

Description

Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Additional splice variants may exist for this gene, but they have not been fully described. [provided by RefSeq

Sequence: SGHDNRVSCLGVT

Specifications

• Antigen: GNB3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:16000) Western Blot (0.1-0.3 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: GNB3
• Gene Symbols: GNB3
• Immunogen: A synthetic peptide corresponding to amino acids at internal region of human GNB3.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: This antibody is expected to recognize GNB3 & GNB4 (GeneID: 2784, 59345; ProteinID: NP_002066.1; NP_067642.1).
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: ELISA, Western Blot
• Concentration: 0.5 mg/mL
• Description: Goat polyclonal antibody raised against synthetic peptide of GNB3.
• Formulation: In 0.5mg/mL in Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene Accession No.: NP_002066.1;NP_067642.1
• Host Species: Goat
• Purification Method: Antigen affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 2784
• Target Species: Human
• Form: Liquid

For Research Use Only