GJB6, Goat, Polyclonal Antibody, Abnova™

Goat polyclonal antibody raised against synthetic peptide of GJB6.

Brand:  Abnova PAB17269.100ug

Product Code. 16092697

Description

Gap junctions allow the transport of ions and metabolites between the cytoplasm of adjacent cells. They are formed by two hemichannels, made up of six connexin proteins assembled in groups. Each connexin protein has four transmembrane segments, two extracellular loops, a cytoplasmic loop formed between the two inner transmembrane segments, and the N- and C-terminus both being in the cytoplasm. The specificity of the gap junction is determined by which connexin proteins comprise the hemichannel. In the past, connexin protein names were based on their molecular weight, however the new nomenclature uses sequential numbers based on which form (alpha or beta) of the gap junction is present. This gene encodes one of the connexin proteins. Mutations in this gene have been found in some forms of deafness and in some families with hidrotic ectodermal dysplasia. [provided by RefSeq

Sequence: C-RSKRAQTQKNHPNH

Specifications

• Antigen: GJB6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:16000) The optimal working dilution should be determined by the end user.
• Gene: GJB6
• Gene Alias: CX30/DFNA3/ED2/EDH/HED
• Host Species: Goat
• Purification Method: Antigen affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 10804
• Target Species: Human
• Form: Liquid

• Applications: ELISA
• Concentration: 0.5 mg/mL
• Description: Goat polyclonal antibody raised against synthetic peptide of GJB6.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene Accession No.: NP_006774.2
• Gene Symbols: GJB6
• Immunogen: A synthetic peptide corresponding to amino acids at internal region of human GJB6.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: Reported variants represent identical protein: NP_006774.2, NP_001103691.1, NP_001103689.1, NP_001103690.1
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only