DUSP10, Goat, Polyclonal Antibody, Abnova™

Goat polyclonal antibody raised against synthetic peptide of DUSP10.

Brand:  Abnova PAB6116.100ug

Product Code. 16089407

Description

Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAPK superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAPKs, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK, but not MAPK/ERK. Its subcellular localization is unique; it is evenly distributed in both the cytoplasm and the nucleus. This gene is widely expressed in various tissues and organs, and its expression is elevated by stress stimuli. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq

Sequence: CRILTPKLMGVETVV

Specifications

• Antigen: DUSP10
• Classification: Polyclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:8000) Western blot (0.5-2 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: DUSP10
• Gene Alias: MKP-5/MKP5
• Host Species: Goat
• Purification Method: Antigen affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 11221
• Target Species: Human
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.5 mg/mL
• Description: Goat polyclonal antibody raised against synthetic peptide of DUSP10.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene Accession No.: NP_009138.1;NP_653329.1;NP_653330.1
• Gene Symbols: DUSP10
• Immunogen: A synthetic peptide corresponding to human DUSP10.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: This antibody is expected to recognize both reported human isofoms. NP_653329.1 and NP_653330.1 are varients that encode the same isoform.
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only