ANTXR1, Goat, Polyclonal Antibody, Abnova™

Goat polyclonal antibody raised against synthetic peptide of ANTXR1.

Brand:  Abnova PAB6677.100ug

Product Code. 16019847

Description

This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq

Sequence: C-RAPPPSRPPPRPSV

Specifications

• Antigen: ANTXR1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:64000) Western Blot (0.2-1 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: ANTXR1
• Gene Alias: ATR/FLJ10601/FLJ11298/FLJ21776/TEM8
• Host Species: Goat
• Purification Method: Antigen affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 84168
• Target Species: Human
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.5 mg/mL
• Description: Goat polyclonal antibody raised against synthetic peptide of ANTXR1.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene Accession No.: NP_115584
• Gene Symbols: ANTXR1
• Immunogen: A synthetic peptide corresponding to human ANTXR1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: This antibody is expected to recognize variant 1 (NP_115584) only.
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only