GNRHR Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 22462-1-AP-20UL

Product Code. 16871945

Description

This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5 region and multiple polyA signals in the 3 region have been identified for this gene.

Specifications

• Antigen: GNRHR
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GNRHR
• Gene Alias: GnRH R, GnRH receptor, GNRHR, GNRHR1, GRHR, LHRHR, LRHR
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14715, 2798, 81668
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.13 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P30968, P30969, Q01776
• Gene Symbols: Gnrhr
• Immunogen: GNRHR Fusion Protein Ag18005
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat, Mouse
• Product Type: Antibody
• Isotype: IgG