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  6. Invitrogen™ GNE Recombinant Rabbit Monoclonal Antibody (K01_1R67)

Invitrogen™ GNE Recombinant Rabbit Monoclonal Antibody (K01_1R67)

Product Code. 30827309
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30827309 50 μL
30830115 100 μL
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Product Code. 30827309 Supplier Invitrogen™ Supplier No. MA565150

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Description

Rabbit Recombinant Monoclonal Antibody

GNE Recombinant Monoclonal Antibody for Western Blot

GNE is a bifunctional enzyme that initiates and regulates the biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate-limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction. Differential sialylation of cell surface molecules is also implicated in the tumorigenicity and metastatic behavior of malignant cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GNE
Applications Western Blot
Classification Recombinant Monoclonal
Clone K01_1R67
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 50mM tris glycine with 40% glycerol, 150mM NaCl, 0.05% BSA and 0.01% sodium azide; pH 7.4
Gene GNE
Gene Accession No. Q9Y223
Gene Alias 2310066H07Rik; bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase; DMRV; GLCNE; glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase; GNE; IBM2; ManAc kinase; N-acetylmannosamine kinase; N-acylmannosamine kinase; NM; Uae1; UDP-GlcNAc-2-epimerase; UDP-GlcNAc-2-epimerase/ManAc kinase; UDP-N-acetylglucosamine 2-epimerase (hydrolyzing); UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase; UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase; Uridine diphosphate-N-acetylglucosamine-2-epimerase
Gene Symbols GNE
Host Species Rabbit
Immunogen A synthetic peptide of human GLCNE.
Purification Method Protein A/G
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10020
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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