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GNE-272, MedChemExpress

Product Code. 16479686
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Product Code. 16479686

missing translation for 'mfr': Medchem Express HY100726

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Description

MedChemExpress GNE-272 is a potent and selective CBP/EP300 inhibitor with IC50 values of 0.02, 0.03 and 13 μM for CBP, EP300 and BRD4, respectively. GNE-272 is also a selective in vivo probe for CBP/EP300.

GNE-272 is a potent and selective CBP/EP300 inhibitor with IC50 values of 0.02, 0.03 and 13 μM for CBP, EP300 and BRD4, respectively. GNE-272 is also a selective in vivo probe for CBP/EP300.

Specifications

Chemical Name or Material GNE-272
CAS 1936428-93-1
Color White
Purity Grade Notes Research
Molecular Formula C22H25FN6O2
Quantity 50 mg
Solubility Information DMSO : 100 mg/mL (235.59 mM; Need ultrasonic)
SMILES CC(N1CCC2=C(C(NC3=C(F)C=C(C4=CN(C)N=C4)C=C3)=NN2[C@@H]5COCC5)C1)=O
Molecular Weight (g/mol) 424.47
Formula Weight 424.47
Percent Purity 99.74%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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