GNB1L Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA556996

Product Code. 15784891

Description

Immunogen sequence: VDSVCLESVG FCRSSILAGG QPRWTLAVPG RGSDEVQILE MPSKTSVCAL KPKADAKLGM PMCLRLWQAD CSSRPLLLAG YEDGSVVL Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 78%.

GNB1L is a G-protein beta-subunit-like polypeptide which is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 6 WD repeats and is highly expressed in the heart. Therefore, this gene may contribute to the etiology of those disorders.This gene encodes a G-protein beta-subunit-like polypeptide which is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 6 WD repeats and is highly expressed in the heart. The gene maps to the region on chromosome 22q11, which is deleted in DiGeorge syndrome, trisomic in derivative 22 syndrome and tetrasomic in cat-eye syndrome. Therefore, this gene may contribute to the etiology of those disorders.

Specifications

• Antigen: GNB1L
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GNB1L
• Gene Alias: DGCRK3; Estm55; FKSG1; G protein subunit beta 1 like; g protein subunit beta-like protein 1; Gm16314; Gnb1l; G-protein beta subunit-like protein; guanine nucleotide binding protein (G protein), beta polypeptide 1-like; guanine nucleotide binding protein beta-subunit-like polypeptide; guanine nucleotide-binding protein subunit beta-like protein 1; GY2; KIAA1645; Me49f07; OTTMUSG00000033458; WD repeat-containing protein 14; WD40 repeat-containing protein deleted in VCFS; Wdr14; WDVCF; zgc:110763
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 54584
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9BYB4
• Gene Symbols: GNB1L
• Immunogen: Recombinant protein corresponding to Human GNB1L
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Research Use Only