Invitrogen™ GLYR1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA562141

Product Code. 15729941

Description

Immunogen sequence: KCYVDMSTVD ADTVTELAQV IVSRGGRFLE APVSGNQQLS NDGMLVILAA GDRGLYEDCS SCFQAMGKTS FFLGEVGNAA KMMLIV Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

GLYR1 may have oxidoreductase activity. It regulates p38 MAP kinase activity by mediating stress activation of p38alpha/MAPK14 and specifically regulating MAPK14 signaling. It indirectly promotes phosphorylation of MAPK14 and activation of ATF2. The phosphorylation of MAPK14 requires upstream activity of MAP2K4 and MAP2K6. It is recruited on chromatin, recognizes and binds trimethylated 'Lys-36' of histone H3 (H3K36me3).

Specifications

• Antigen: GLYR1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GLYR1
• Gene Alias: 2810419J22Rik; 3930401k13rik; 3-hydroxyisobutyrate dehydrogenase-like protein; AW545332; BM045; Cytokine-like nuclear factor N-PAC; glyoxylate reductase 1 homolog; glyoxylate reductase 1 homolog (Arabidopsis); GLYR1; HIBDL; hNDF; NDF; NP60; Npac; N-pac; nuclear protein 60 kDa; nuclear protein 60kDa; nuclear protein NP60; Nuclear protein of 60 kDa; Nucleosome-destabilizing factor; Putative oxidoreductase GLYR1; RGD1309459
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 84656
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q49A26
• Gene Symbols: GLYR1
• Immunogen: Recombinant protein corresponding to Human GLYR1. Recombinant protein control fragment (Product #RP-103065).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG