Glycoprotein VI Mouse anti-Human, eFluor 660, Clone: HY101, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 50-9813-42
Code : NEW
Additional Details : Weight : 0.23750kg
DescriptionThe HY101 monoclonal antibody reacts with the glycoprotein VI (GPVI), a 62kDa type-I transmembrane glycoprotein that is expressed on mature megakaryotes and platelets. GPVI associates with the Fc receptor (FcR) gamma-chain to form a high affinity receptor for collagen. GPVI has also been reported to bind convulxin (Cvx). Phosphorylation of the ITAMs present on the FcR gamma-chain leads to recruitment of Src family kinases and activation of downstream signal transduction. GPVI has been reported to play a critical role in platelet activation and aggregation.
|aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer|
|Store at 2-8°C. Do not freeze. Light-sensitive material.|