Glycoprotein VI Mouse anti-Human, eFluor 660, Clone: HY101, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 50-9813-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15510147

Quantity Price
1 £ 131.46 / 100 tests
Estimated Shipment date
from Supplier 07-06-2017
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Description and Specification

Specification

Antigen Glycoprotein VI
Applications Flow Cytometry
Clone HY101
Concentration 5μL (0.25μg)/test
Conjugate eFluor 660
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias GPVI, GP6
Host Species Murine
Isotype IgG1
Quantity 100 Tests
Regulatory Status RUO
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Target Species Human

The HY101 monoclonal antibody reacts with the glycoprotein VI (GPVI), a 62kDa type-I transmembrane glycoprotein that is expressed on mature megakaryotes and platelets. GPVI associates with the Fc receptor (FcR) gamma-chain to form a high affinity receptor for collagen. GPVI has also been reported to bind convulxin (Cvx). Phosphorylation of the ITAMs present on the FcR gamma-chain leads to recruitment of Src family kinases and activation of downstream signal transduction. GPVI has been reported to play a critical role in platelet activation and aggregation.