Glycoprotein VI Mouse anti-Human, eFluor 660, Clone: HY101, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 50-9813-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15510147

Quantity Price
1 £ 131.46 / 100 tests
Estimated Shipment date
from Supplier 03-04-2017
Add to basket


Description and Specification

Specification

Primary or Secondary Primary
Applications Flow Cytometry
Isotype IgG1
Quantity 100 tests
Gene Alias GPVI, GP6
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Clone HY101
Format Conjugated
Host Species Mouse
Species Reactivity Human
Concentration 5μL (0.25μg)/test
Monoclonal or Polyclonal Monoclonal
Conjugate eFluor 660
Regulatory Status RUO
Antigen Glycoprotein VI
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer

The HY101 monoclonal antibody reacts with the glycoprotein VI (GPVI), a 62kDa type-I transmembrane glycoprotein that is expressed on mature megakaryotes and platelets. GPVI associates with the Fc receptor (FcR) gamma-chain to form a high affinity receptor for collagen. GPVI has also been reported to bind convulxin (Cvx). Phosphorylation of the ITAMs present on the FcR gamma-chain leads to recruitment of Src family kinases and activation of downstream signal transduction. GPVI has been reported to play a critical role in platelet activation and aggregation.