Invitrogen™ GLYATL1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA558816

Product Code. 15716691

Description

Immunogen sequence: QGLQESLGEG IRVATFSKSV KVEHSRALLL VTEDILKLNA SSKSKLGSWA ETGHPDDEFE SETPNFKYAQ Highest antigen sequence identity to the following orthologs: Mouse - 27%, Rat - 28%.

The GLYATL1 gene, also known as Glycine-N-Acyltransferase Like 1, is located on chromosome 11q12.1. This gene encodes a member of the glycine-N-acyltransferase family, which is involved in the detoxification pathway by catalyzing the conjugation of acyl-CoA substrates with glycine. The protein encoded by GLYATL1 is localized to the endoplasmic reticulum and is implicated in various cellular processes, including xenobiotic metabolism and mitochondrial glutamine metabolism. Studies have shown that the expression levels of GLYATL1 are significantly associated with cancer prognosis. For example, decreased expression of GLYATL1 has been linked to poor prognosis in patients with clear cell renal cell carcinoma (ccRCC). Furthermore, differential expression analysis has identified GLYATL1 as a potential biomarker in prostate cancer, suggesting its utility in cancer diagnostics and treatment strategies. The gene comprises multiple exons and undergoes alternative splicing, resulting in various transcript variants.

Specifications

• Antigen: GLYATL1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GLYATL1
• Gene Alias: acyl-CoA:glycine N-acyltransferase-like protein 1; GATF-C; Glutamine N-acyltransferase; GLYATL1; Glycine N-acyltransferase-like protein 1; glycine-N-acyltransferase like 1; glycine-N-acyltransferase-like 1; GNAT; RGD1564894; uncharacterized protein LOC309227
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 92292
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q969I3
• Gene Symbols: GLYATL1
• Immunogen: Recombinant protein corresponding to Human GLYATL1. Recombinant protein control fragment (Product #RP-97458).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG