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Glutaminase-IN-1, MedChemExpress

Product Code. 16497557
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Product Code. 16497557

Brand: Medchem Express HY1143345mg

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MedChemExpress Glutaminase-IN-1 (CB839 derivative), a CB839 derivative, is an allosteric inhibitor of 1,3,4-selenadiazole-containing kidney-type glutaminase (KGA), with an IC50 of 1 nM. Glutaminase-IN-1 (CB839 derivative) shows improved cellular uptake and antitumor activity.

Glutaminase-IN-1 (CB839 derivative), a CB839 derivative, is an allosteric inhibitor of 1,3,4-selenadiazole-containing kidney-type glutaminase (KGA), with an IC50 of 1 nM. Glutaminase-IN-1 (CB839 derivative) shows improved cellular uptake and antitumor activity.

Specifications

Chemical Name or Material Glutaminase-IN-1
CAS 2247127-79-1
Color Yellow
Purity Grade Notes Research
Molecular Formula C26H24F3N7O3Se
Quantity 5 mg
Synonym CB839 derivative
Solubility Information DMSO : 125 mg/mL (202.11 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (insoluble)
SMILES O=C(NC1=NN=C(CCCCC2=NN=C(NC(CC3=CC=CC(OC(F)(F)F)=C3)=O)C=C2)[Se]1)CC4=NC=CC=C4
Molecular Weight (g/mol) 618.47
Formula Weight 618.47
Percent Purity 98.65%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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