Invitrogen™ GluR7 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA520450

Product Code. 12808632

Description

A suggested positive control is human brain tissue lysate. PA5-20450 can be used with blocking peptide PEP-0567.

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics.

Specifications

• Antigen: GluR7
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GRIK3
• Gene Alias: 9630027E11; dJ1090M5.1 (glutamate receptor, ionotropic, kainate 3 (GLUR7)); EAA5; Excitatory amino acid receptor 5; GLR7; GluK3; GLUR7; Glur-7; GluR7-3; GluR7a; glutamate ionotropic receptor kainate type subunit 3; glutamate receptor; glutamate receptor 7; Glutamate receptor ionotropic, kainate 3; glutamate receptor subunit kainate subtype; glutamate receptor, ionotropic, kainate 3; Grik3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14807, 2899, 298521
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: B1AS29, P42264, Q13003
• Gene Symbols: GRIK3
• Immunogen: A 13 amino acid peptide near the amino terminus of the human Grik3.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG