Invitrogen™ GluR4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA524217

Product Code. 13262089

Description

This antibody is predicted to react with non-human primate and rat based on sequence homology.

Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate, whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions.

Specifications

• Antigen: GluR4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Gria4
• Gene Alias: AMPA-selective glutamate receptor 4; GluA4; GLUR4; Glur-4; GLUR4C; Gluralpha4; GLURD; GluR-D; glutamate ionotropic receptor AMPA type subunit 4; glutamate receptor; glutamate receptor 4; glutamate receptor channel alpha 4; glutamate receptor ionotropic, AMPA 4; glutamate receptor, ionotrophic, AMPA 4; glutamate receptor, ionotropic, AMPA 4; glutamate receptor, ionotropic, AMPA4 (alpha 4); Gria4; spike wave 1; spkw1
• Host Species: Rabbit
• Purification Method: Protein A, Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14802, 2893
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: P48058, Q9Z2W8
• Gene Symbols: Gria4
• Immunogen: KLH conjugated synthetic peptide between 259-287 amino acids from the central region of human GRIA4.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG