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Invitrogen™ GluR3 Monoclonal Antibody (1D2)
Description
MA5-15869 targets GRIA3 in indirect ELISA, IHC and WB applications and shows reactivity with Human samples. The MA5-15869 immunogen is purified recombinant fragment of human GRIA3 expressed in E. Coli. . MA5-15869 detects GRIA3 which has a predicted molecular weight of approximately 101kDa.
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties.
Specifications
Specifications
| Antigen | GluR3 |
| Applications | ELISA, Immunohistochemistry (Paraffin), Western Blot |
| Classification | Monoclonal |
| Clone | 1D2 |
| Concentration | Conc. Not Determined |
| Conjugate | Unconjugated |
| Formulation | Ascites with 0.03% sodium azide |
| Gene | GRIA3 |
| Gene Accession No. | P42263 |
| Gene Alias | 2900064I19Rik; AMPA-selective glutamate receptor 3; dJ1171F9.1; GluA3; GLUR3; Glur-3; Gluralpha3; GLURC; GLUR-C; GluR-K3; glutamate ionotropic receptor AMPA type subunit 3; glutamate receptor; glutamate receptor 3; glutamate receptor C; glutamate receptor channel alpha3 subunit; Glutamate receptor ionotropic, AMPA 3; glutamate receptor subunit 3; glutamate receptor, ionotrophic, AMPA 3; glutamate receptor, ionotropic, AMPA 3; glutamate receptor, ionotropic, AMPA3 (alpha 3); GRIA3; Kiaa4184; LOW QUALITY PROTEIN: glutamate receptor 3; MRX94; OTTHUMP00000024262; RP11-349N19.3 |
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