GLRX2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 13381-1-AP-20UL

Product Code. 16821564

Description

Glutaredoxin (Grx), also known as thiol transferase, is a small heat-stable oxidoreductase. Grxs form part of the glutaredoxin system, comprising NADPH, GSH and glutathione reductase, which transfers electrons from NADPH to glutaredoxins via GSH. First discovered in E. coli as GSH-dependent hydrogen donors for ribonucleotide reductase, Grx catalyzes GSH-disulfide oxidoreductase via two redox-active cysteine residues. The active sequence (Cys-Pro-Tyr-Cys) is conserved in a variety of species. The 12-kDa dithiol protein has a role in reduction of mixed disulfides in cells exposed to oxidative stress.

Specifications

• Antigen: GLRX2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GLRX2
• Gene Alias: GLRX2, Glutaredoxin 2, Glutaredoxin 2, mitochondrial, GRX2
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 114022, 51022, 69367
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry, Immunofluorescence
• Concentration: 0.37 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q6AXW1, Q923X4, Q9NS18
• Gene Symbols: GLRX2
• Immunogen: GLRX2 Fusion Protein Ag4218
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat, Mouse
• Product Type: Antibody
• Isotype: IgG