Invitrogen™ GLRX2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA544837

Product Code. 15596652

Description

Peptide sequence: NVNYKVVELD LLEYGNQFQD ALYKMTGERT VPRIFVNGTF IGGATDTHRL H Sequence homology: Cow: 86%; Dog: 86%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 93%; Rabbit: 86%; Rat: 86%; Sheep: 86%.

Glutaredoxin (Grx), also known as thiol transferase, is a small heat-stable oxidoreductase. Grxs form part of the glutaredoxin system, comprising NADPH, GSH and glutathione reductase, which transfers electrons from NADPH to glutaredoxins via GSH. First discovered in E. coli as GSH-dependent hydrogen donors for ribonucleotide reductase, Grx catalyzes GSH-disulfide oxidoreductase via two redox-active cysteine residues. The active sequence (Cys-Pro-Tyr-Cys) is conserved in a variety of species. The 12-kD dithiol protein has a role in reduction of mixed disulfides in cells exposed to oxidative stress.

Specifications

• Antigen: GLRX2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GLRX2
• Gene Alias: 1700010P22Rik; AI645710; bA101E13.1 (GRX2 glutaredoxin (thioltransferase) 2); CGI-133; GLRX2; glutaredoxin (thioltransferase) 2; glutaredoxin 2; glutaredoxin 2 (thioltransferase); glutaredoxin-2, mitochondrial; GRX2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51022
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q9NS18
• Gene Symbols: GLRX2
• Immunogen: Synthetic peptide directed towards the middle region of human GLRX2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG