Invitrogen™ GLP2R Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA576959

Product Code. 15933475

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

The GLP2 receptor (GLP2R) is a G protein-coupled receptor superfamily member closely related to the glucagon receptor ans GLP1 receptor. Glucagon-like peptide-2 (GLP2) is a 33-amino acid proglucagon-derived peptide produced by intestinal enteroendocrine cells. Like glucagon-like peptide-1 (GLP1) and glucagon itself, it is derived from the proglucagon peptide encoded by the GCG gene. GLP2 stimulates intestinal growth and upregulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. Moreover, GLP2 prevents intestinal hypoplasia resulting from total parenteral nutrition. GLP2R, a G protein-coupled receptor superfamily member is expressed in the gut and closely related to the glucagon receptor (GCGR) and the receptor for GLP1 (GLP1R).

Specifications

• Antigen: GLP2R
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GLP2R
• Gene Alias: 9530092J08Rik; G protein-coupled receptor GLP2R; GLP-2; Glp2 receptor; GLP-2 receptor; GLP2R; GLP-2R; GLP-2-R; glucagon like peptide 2 receptor; glucagon-like peptide 2 receptor; glucagon-like peptide-2 receptor
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9340, 93896
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: TBS with 1% BSA, 50% glycerol and 0.03% ProClin 300; pH 7.4
• Gene Accession No.: O95838, Q5IXF8
• Gene Symbols: GLP2R
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 460-553 of human GLP2R.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG