Invitrogen™ GLP-1 Monoclonal Antibody (53)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ ABS0445302

Product Code. 15356291

Description

Specificity: ABS 044-53-02 binds human GLP-1 (9-36) amide. Based on inhibition ELISA, this antibody shows less than 2% cross-Specificity with GLP-1 (7-36) amide. Reactivity: ABS 044-53-02 binds free GLP-1 (9-36) amide in solution. This product has a higher affinity for GLP-1 (9-36) amide than ABS 044-49-02 as determined by an Inhibition assay. NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL.

GCG is also known as GLP1, or Glucagon. Glucagon is a 29-amino acid pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis.It is mapped to 2q36-2q37. GLP1, also known as 7-37 for the codons of the preproglucagon molecule which encode it, renders pancreatic beta-cells 'glucose-competent' and may be useful in the treatment of noninsulin-dependent diabetes mellitus. Also, GLP1 is a potent insulin secretagogue.It plays a major role in the enteroinsular axis, accounting, for example, for the finding that plasma insulin levels accompanying oral intake of glucose are greater than those observed when glucose is given intravenously.

Specifications

• Antigen: GLP-1
• Classification: Monoclonal
• Concentration: 1.15 mg/mL
• Formulation: PBS with 15mM sodium azide; pH 7.4
• Gene Accession No.: P01275
• Gene Symbols: GCG
• Immunogen: Synthetic GLP-1(9-18) adsorbed onto aluminum hydroxide gel.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: ELISA, Western Blot
• Clone: 53
• Conjugate: Unconjugated
• Gene: GCG
• Gene Alias: GCG; Glicentin; Glicentin-related polypeptide; GLP1; GLP-1; GLP-1(7-36); GLP-1(7-37); GLP1/2; GLP2; GLP-2; Glu; glucagon; Glucagon like peptide 1; Glucagon-like peptide 1; Glucagon-like peptide 1(7-36); Glucagon-like peptide 1(7-37); Glucagon-like peptide 2; glucagon-like peptide-1; GRPP; Incretin hormone; MGC138331; OXM; OXY; Oxyntomodulin; PPG; preproglucagon
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 2641
• Content And Storage: 4°C, store in dark
• Form: Liquid