Invitrogen™ GLIS3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Marca:  Invitrogen™ PA541677

Codice prodotto. 15544952

Descrizione

Peptide sequence: PPASQVSTAC NQISPSLQRA MNAANLNIPP SDTRSLISRE SLASTTLSLT Sequence homology: Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%.

This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear protein with five C2H2-type zinc finger domains. This protein functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells, the thyroid, eye, liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH). Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only two have been determined.

Specifica

• Antigen: GLIS3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GLIS3
• Gene Alias: 4833409N03Rik; E330013K21Rik; GLIS family zinc finger 3; Glis3; GLI-similar 3; NDH; OK/KNS-cl.4; RGD1565505; Zinc finger protein 515; zinc finger protein GLIS3; ZNF515
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 169792
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q8NEA6
• Gene Symbols: GLIS3
• Immunogen: Synthetic peptide directed towards the N-terminal of human GLIS3 (aa 11-60).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG