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Glibenclamide, MedChemExpress

Product Code. 16431489
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Quantity:
1 g
5 g
Unit Size:
1g
5g
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Product Code. 16431489

Brand: Medchem Express HY15206

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Description

MedChemExpress Glibenclamide (Glyburide) is an orally active ATP-sensitive K+ channel (KATP) inhibitor and can be used for the research of diabetes and obesity.

Glibenclamide inhibits P-glycoprotein. Glibenclamide directly binds and blocks the SUR1 subunits of KATP and inhibits the cystic fibrosis transmembrane conductance regulator protein (CFTR). Glibenclamide interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability. Glibenclamide can induce autophagy.

Specifications

Chemical Name or Material Glibenclamide
CAS 10238-21-8
Color White
Purity Grade Notes Research
Molecular Formula C23H28ClN3O5S
Quantity 1 g
Synonym Glyburide
Solubility Information DMSO : 250 mg/mL (506.07 mM; Need ultrasonic) ∣H2O : 0.1 mg/mL (0.20 mM; Need ultrasonic and warming)
SMILES ClC1=CC(C(NCCC2=CC=C(S(NC(NC3CCCCC3)=O)(=O)=O)C=C2)=O)=C(OC)C=C1
Molecular Weight (g/mol) 494.0
Formula Weight 494.0
Percent Purity 98.89%
Grade Research
Physical Form Solid
For Use With (Application) Metabolism-protein/nucleotide metabolism
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Research purposes only

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