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Glesatinib hydrochloride, MedChemExpress

Product Code. 16497656
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Product Code. 16497656 Supplier Medchem Express Supplier No. HY19642A

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Description

MedChemExpress Glesatinib hydrochloride (MGCD265 hydrochloride) is an orally active, potent MET/SMO dual inhibitor. Glesatinib hydrochloride, a tyrosine kinase inhibitor, antagonizes P-glycoprotein (P-gp) mediated multidrug resistance (MDR) in non-small cell lung cancer (NSCLC).

Glesatinib hydrochloride (MGCD265 hydrochloride) is an orally active, potent MET/SMO dual inhibitor. Glesatinib hydrochloride, a tyrosine kinase inhibitor, antagonizes P-glycoprotein (P-gp) mediated multidrug resistance (MDR) in non-small cell lung cancer (NSCLC).

Specifications

Chemical Name or Material Glesatinib hydrochloride
CAS 1123838-51-6
Color Pink
Purity Grade Notes Research
Molecular Formula C31H28ClF2N5O3S2
Quantity 100 mg
Synonym MGCD265 hydrochloride
Solubility Information DMSO : 50 mg/mL (76.20 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
SMILES O=C(NC(NC1=CC=C(OC2=C3C(C=C(C4=NC=C(CNCCOC)C=C4)S3)=NC=C2)C(F)=C1)=S)CC5=CC=C(F)C=C5.Cl
Molecular Weight (g/mol) 656.17
Formula Weight 656.17
Percent Purity 98.0%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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