Invitrogen™ GLD2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA589106

Product Code. 16517131

Description

Immunogen sequence: MFPNSILGRP PFTPNHQQHN NFFTLSPTVY SHQQLIDAQF NFQNADLSRA VSLQQLTYGN VSPIQTSASP LFRGRKRLSD EKNLPLDGKR QRFHSPHQEP TVVNQIVPLS GERRYSMPPL FHTHYVPDIV RCVPPFREIA FLEPREITLP EAKDKLSQQI LELFETCQQQ ISDLKKKELC RTQLQREIQL LFPQSRLFLV GSSLNGFGTR SSDGDLCLVV KEEPCFFQVN QKTEARHILT LVHKHFCTRL SGYIERPQLI RAKVPIVKFR DKVSCVEFDL NVNNIVGIRN TFLLRTYAYL; Positive Samples: U-87MG, BxPC-3, Mouse heart, Rat heart; Cellular Location: Cytoplasm, Nucleus.

GLD2 is cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. In contrast to the canonical nuclear poly(A) RNA polymerase, it only adds poly(A) to selected cytoplasmic mRNAs. GLD2 does not play a role in replication-dependent histone mRNA degradation.

Specifications

• Antigen: GLD2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Papd4
• Gene Alias: 8030446C20Rik; AI649009; cytoplasmic poly(A) polymerase; Gld2; GLD-2; hGLD-2; hypothetical protein LOC553626; MGC138008 protein; mGLD-2; Palp4; PAP associated domain containing 4; PAP-associated domain-containing protein 4; PAPD4; poly(A) RNA polymerase D4, non-canonical; Poly(A) RNA polymerase GLD2; Tent2; Terminal nucleotidyltransferase 2; terminal uridylyltransferase 2; TUT2; TUTase 2; TUTase2; zgc:110560
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100715, 167153, 361878
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.88 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q5U315, Q6PIY7, Q91YI6
• Gene Symbols: Papd4
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PAPD4 (NP_7761582).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG