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Glasdegib, MedChemExpress

Product Code. 16467096
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Product Code. 16467096 Supplier Medchem Express Supplier No. HY16391

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Description

MedChemExpress Glasdegib (PF-04449913) is a potent and orally bioavailable smoothened inhibitor. Glasdegib (PF-04449913) binds to human SMO (amino acids 181-787) with an IC50 of 4 nM.

Glasdegib (PF-04449913) is a potent and orally bioavailable smoothened inhibitor. Glasdegib (PF-04449913) binds to human SMO (amino acids 181-787) with an IC50 of 4 nM.

Specifications

Chemical Name or Material Glasdegib
CAS 1095173-27-5
Color White
Purity Grade Notes Research
Molecular Formula C21H22N6O
Quantity 100 mg
Synonym PF-04449913
Solubility Information DMSO : ≥ 83.33 mg/mL (222.55 mM)
SMILES O=C(NC1=CC=C(C#N)C=C1)N[C@H]2C[C@H](C3=NC4=CC=CC=C4N3)N(C)CC2
Molecular Weight (g/mol) 374.44
Formula Weight 374.44
Percent Purity 98.36%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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