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GKI-1, MedChemExpress

Product Code. 16493058
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Quantity:
5 mg
10 mg
Unit Size:
10mg
5mg
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Product Code. 16493058

Brand: Medchem Express HY100521

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Description

MedChemExpress GKI-1 is a Greatwall (GWL) kinase inhibitor with IC50s of 4.9 and 2.5 μM against hGWLFL and hGWL-KinDom, respectively. GKI-1 robustly inhibits ROCK1 with an IC50 of 11 μM, but only weakly affected PKA.

GKI-1 is a Greatwall (GWL) kinase inhibitor with IC50s of 4.9 and 2.5 μM against hGWLFL and hGWL-KinDom, respectively. GKI-1 robustly inhibits ROCK1 with an IC50 of 11 μM, but only weakly affected PKA.

Specifications

Chemical Name or Material GKI-1
Physical Form Solid
CAS 2444764-03-6
Color Off-White
Quantity 10 mg
Purity Grade Notes Research
Molecular Formula C15H12ClN3
For Use With (Application) Cancer-Kinase/protease
Solubility Information DMSO : 200 mg/mL (741.48 mM; Need ultrasonic)
SMILES ClC(C=C1)=CC=C1NC2=CC(C3=CNN=C3)=CC=C2
Molecular Weight (g/mol) 269.73
Formula Weight 269.73
Percent Purity 98.02%
Grade Research
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Research purposes only

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