Invitrogen™ GIPR Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA533586

Product Code. 15324521

Description

BLAST analysis of the peptide immunogen showed 100% homology with human protein GHRHR. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey (100%) Marmoset (95%) Dog, Hamster, Panda (89%) Mouse, Rat, Rabbit (84%).

GIPR encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes.

Specifications

• Antigen: GIPR
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GIPR
• Gene Alias: gastric inhibitory peptide receptor; gastric inhibitory polypeptide receptor; GIP receptor; Gippr; Gipr; GIP-R; Glucose-dependent insulinotropic polypeptide receptor; Gm1081; Gm160; PGQTL2; RATGIPPR
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2696
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: P48546
• Gene Symbols: GIPR
• Immunogen: Synthetic 19 amino acid peptide from N-terminal extracellular domain of human GIPR.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG