GIPR (extracellular) Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA577447

Product Code. 15923955

Description

Product is shipped at room temperature as a lyophilized powder and should be stored at -20 °C upon receipt. Reconstitution: add 50 μL of deionized water.

This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes.

Specifications

• Antigen: GIPR (extracellular)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Gipr
• Gene Alias: Gastric Inhibitory Polypeptide Receptor (extracellular)
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 25024, 381853
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Immunofluorescence, Immunohistochemistry (Frozen), Western Blot
• Concentration: 0.8 mg/mL
• Formulation: PBS with 1% BSA and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P43219, Q0P543
• Gene Symbols: Gipr
• Immunogen: Peptide (C)EGQTTGELYQRWER, corresponding to amino acid residues 25-38 of rat Gastric Inhibitory Polypeptide Receptor
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG