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GILZ Rat anti-Mouse, Clone: CFMKG15, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-4033-82

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15297347

  • £152.25 / 100µg


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For Research Use Only.


Description

Description

GILZ is a leucine-zipper-containing protein that is induced by glucocorticoids. It is expressed in mast cells, monocytes, macrophages, dendritic cells, and T cells. GILZ has been shown to inhibit production of IL-2 as well as TCR-driven upregulation of FasL. GILZ mediates these changes in transcription, at least in part, by inhibiting DNA-binding of the transcription factors AP-1 and NF-κB. GILZ has also been shown to mediate anti-inflammatory signals in macrophages and dendritic cells by interfering with NF-κB-mediated signaling. Although GILZ has been reported to localize to the nucleus, more recent reports as well as testing at eBioscience have observed predominantly cytoplasmic staining.
Specifications

Specifications

GILZ
CFMKG15
Unconjugated
Purified
Rat
100μg
Store at 2-8°C.
Monoclonal
Western Blot
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Glucocorticoid-Induced Leucine Zipper, TSC22D3
IgG2a
RUO
Primary
Murine
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