Gibco™ BMP2 Recombinant Human Protein

Recombinant Human Bone Morphogenetic Protein 2 (BMP2) is a bioactive protein intended for use in cell culture applications

Overview
Brand: Gibco™

Manufacturer Part Number: PHC7143

UNSPSC: 12352202

Code: 50

Additional Details:
Additional Details: Weight: 0.10000kg



Disclaimers: For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

Product Code. 10329114

Quantity Price
1 £ 4700.0 / Each
Estimated Shipment date
from Supplier 10-04-2017
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For Research Use Only. All usage must comply with product instructions.
 

Description and Specification

Specification

Gene ID (Entrez) 548717
Gene Alias BMP-2, BMP-2, mgC114605, xBMP-2, xbmp2
Structural Form Recombinant/Ligand
Expression System E. coli
Purification Method Sequential Chromatography
Accession Number NM001200
Storage Requirements Store lyophilized human BMP-2 at 2° to 8°C, preferably desiccated. Upon reconstitution, apportion into working aliquots and store at ≤ -20°C. Avoid repeated freeze/thaw cycles.
Purity 95%
Biological Activity ED50 range = 0.1-1.0mg/mL
Validated Application Cell Culture
Endotoxin Concentration <0.1ng/μg
Protein Subtype BMPs (Bone Morphogenetic Proteins) & Related Factors
Quantity 1mg
Molecular Weight 26kDa
Format Lyophilized
Source Human
Cross Reactivity Human
Protein Family Growth Factors & Receptors
Cell Type Stem Cells
Specific Reactivity 1.0 x 104 - 1.0 x103 units/mg
Without Additives Carrier Protein
For Use With (Application) Cell Culture; Mammalian Cell Culture; Cell Analysis; Cell Viability, Proliferation & Function; Cell Proliferation

BMP2 is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. BMP2 acts as a disulfide-linked homodimer and induces bone and cartilage formation.
  • High purity: no interference from other proteins or contaminants
  • High biological activity: more results with less protein
  • Proven compatibility: Gibco proteins bioassayed with Gibco media
  • High Purity Recombinant Bioactive Protein: to help ensure Gibco growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein
  • High Biological Activity: in-house activity testing of Gibco Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, anti-viral, and protease assays; specific activity is determined by the dose dependent induction of alkaline phosphatase in mouse chondrogenic cell line ATDC5
  • Proven Compatibility: Gibco proteins are bioassayed with Gibco media

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