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GGTI-2418, MedChemExpress

Product Code. 16493516
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Product Code. 16493516 Supplier Medchem Express Supplier No. HY16231

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MedChemExpress GGTI-2418 is a highly potent, competitive, and selective geranylgeranyltransferase I (GGTase I) inhibitor. GGTI-2418 inhibits GGTase I and FTase activities with IC50s of 9.5 nM and 53 μM, respectively. GGTI-2418 also increases p27(Kip1) and induces significant regression of breast tumors.

GGTI-2418 is a highly potent, competitive, and selective geranylgeranyltransferase I (GGTase I) inhibitor. GGTI-2418 inhibits GGTase I and FTase activities with IC50s of 9.5 nM and 53 μM, respectively. GGTI-2418 also increases p27(Kip1) and induces significant regression of breast tumors.

Specifications

Chemical Name or Material GGTI-2418
Physical Form Solid
CAS 501010-06-6
Color Light Yellow
Quantity 25 mg
Purity Grade Notes Research
Molecular Formula C23H31N5O4
For Use With (Application) Cancer-Kinase/protease
Solubility Information DMSO : 125 mg/mL (283.11 mM; Need ultrasonic)
SMILES CC(C)C[C@@H](C(O)=O)NC(N1[C@@H](CC2=CC=CC=C2)C(N(CC3=C(C)N=CN3)CC1)=O)=O
Molecular Weight (g/mol) 441.52
Formula Weight 441.52
Percent Purity 98.04%
Grade Research
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