Invitrogen™ GFR alpha-2 Polyclonal Antibody

Goat Polyclonal Antibody

Brand:  Invitrogen™ PA547608

Product Code. 15528102

Description

In direct ELISAs and Western blots, less than 5% cross-reactivity with recombinant human GFR alpha -3 is observed. Reconstitute at 0.2 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.

GFRa-2 binds NTN and mediates activation of RET receptor tyrosine kinase by both NTN and GDNF. Thus, NTN, GFRa-2, and the Ret PTK form a complex to transduce NTN signal and to mediate NTN function.

Specifications

• Antigen: GFR alpha-2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GFRA2
• Gene Alias: GDNF family receptor alpha 2; GDNF family receptor alpha-2; GDNF re; GDNF receptor alpha-2; GDNF receptor beta; GDNFR-alpha-2; Gdnfrb; GDNFR-beta; Gfra2; GFR-alpha 2; GFR-alpha-2; glial cell line derived neurotrophic factor family receptor alpha 2; glial cell line derived neurotrophic factor receptor, beta; HpV18gp1; neurturin receptor alpha; NRTNR-alpha; NTNRA; NTNR-alpha; PI-linked cell-surface accessory protein; RET ligand 2; RETL2; TGF-beta-related neurotrophic factor receptor 2; TRN receptor, GPI-anchored; TRNR2; tyrosine kinase receptor ligand 2
• Host Species: Goat
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14586, 2675
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Frozen), Neutralization, Western Blot, Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: O00451, O08842
• Gene Symbols: GFRA2
• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse GFR alpha-2/GDNF R alpha-2 Ser22-Ser441.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG