Invitrogen™ Gemin 4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA588031

Product Code. 16576371

Description

Immunogen sequence: LREISSAAAH SQPFAWKKKA LIIIWAKVLQ PHPVTPSDTE TRWQEDLFFS VGNMIPTINH TILFELLKSL EASGLFIQLL MALPTTICHA ELERFLEHVT VDTSAEDVAF FLDVWWEVMK HKGHPQDPLL SQFSAMAHKY LPALDEFPHP PKRLRSDPDA CPTMPLLAML LRGLTQIQSR ILGPGRKCCA LANLADMLTV FALTEDDPQE VSATVYLDKL ATVISVWNSD TQNPYHQQAL AEKVKEAERD VSLTSLAKLP SETIFVGCEF LHHLLREWGE ELQAVLRSSQ GTSYDSYRLC D; Positive Samples: HeLa, MCF-7, SH-SY5Y, Jurkat, Mouse brain, Mouse kidney, Mouse liver; Cellular Location: Cytoplasm, Nucleus, gem, nucleolus.

The product of this gene is part of a large complex localized to the cytoplasm, nucleoli, and to discrete nuclear bodies called Gemini bodies. The complex functions in spliceosomal snRNP assembly in the cytoplasm, and regenerates spliceosomes required for pre-mRNA splicing in the nucleus. The encoded protein directly interacts with a DEAD box protein and several spliceosome core proteins. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Specifications

• Antigen: Gemin 4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GEMIN4
• Gene Alias: 4932415L08Rik; AU015359; component of gems 4; DKFZp434B131; DKFZp434D174; gem (nuclear organelle) associated protein 4; gem nuclear organelle associated protein 4; gem-associated protein 4; GEMIN4; Gemin-4; HC56; HCAP1; HCC-associated protein 1; HHRF-1; p97; RGD1563715
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 276919, 50628
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 2.29 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P57678
• Gene Symbols: GEMIN4
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 50-350 of human GEMIN4 (NP_0565362).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG