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Gemcitabine hydrochloride, Tocris Bioscience™
DNA synthesis inhibitor
£134.99 - £455.71
Chemical Identifiers
| CAS | 122111-03-9 |
|---|---|
| Molecular Formula | C9H12ClF2N3O4 |
| Molecular Weight (g/mol) | 299.659 |
| InChI Key | OKKDEIYWILRZIA-OSZBKLCCSA-N |
| Synonym | gemcitabine hcl, 2',2'-difluorodeoxycytidine monohydrochloride, 2'-deoxy-2',2'-difluorocytidine hydrochloride, 2 1h-pyrimidinone, 4-amino-1-2-deoxy-2,2-difluoro-d-erythro-pentofuranosyl |
| PubChem CID | 44558863 |
| ChEBI | CHEBI:31647 |
| IUPAC Name | 4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one;hydron;chloride |
| SMILES | [H+].C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)(F)F.[Cl-] |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
30001393
|
Tocris Bioscience
3259/10 |
10 mg |
£134.99
10mg |
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|
30001403
|
Tocris Bioscience
3259/50 |
50 mg |
£455.71
50mg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
Deoxycytidine analog that inhibits DNA synthesis. Metabolized to form gemcitabine triphosphate (dFdCTP) and gemcitabine diphosphate (dFdCDP). dFdCTD inhibits ribonucleotide reductase causing a reduction in cellular nucleotides. dFdCTP is incorporated in DNA resulting in DNA strand termination. Displays antitumor activity in vitro and in vivo.Chemical Identifiers
| 122111-03-9 | |
| 299.659 | |
| gemcitabine hcl, 2',2'-difluorodeoxycytidine monohydrochloride, 2'-deoxy-2',2'-difluorocytidine hydrochloride, 2 1h-pyrimidinone, 4-amino-1-2-deoxy-2,2-difluoro-d-erythro-pentofuranosyl | |
| CHEBI:31647 | |
| [H+].C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)(F)F.[Cl-] |
| C9H12ClF2N3O4 | |
| OKKDEIYWILRZIA-OSZBKLCCSA-N | |
| 44558863 | |
| 4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one;hydron;chloride |
Specifications
| 122111-03-9 | |
| gemcitabine hcl, 2',2'-difluorodeoxycytidine monohydrochloride, 2'-deoxy-2',2'-difluorocytidine hydrochloride, 2 1h-pyrimidinone, 4-amino-1-2-deoxy-2,2-difluoro-d-erythro-pentofuranosyl | |
| [H+].C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)(F)F.[Cl-] | |
| 299.659 | |
| CHEBI:31647 | |
| >99% |
| C9H12ClF2N3O4 | |
| OKKDEIYWILRZIA-OSZBKLCCSA-N | |
| 4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one;hydron;chloride | |
| 44558863 | |
| 299.66 | |
| Gemcitabine hydrochloride |
Safety and Handling
Recommended Storage : Desiccate at +4°C