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Gefitinib, MedChemExpress

Product Code. p-200096831
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Product Code. 16491926 Supplier Medchem Express Supplier No. HY50895

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Description

MedChemExpress Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy and cell apoptosis, which can be used for cancer related research, such as Lung cancer and breast cancer .

Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy and cell apoptosis, which can be used for cancer related research, such as Lung cancer and breast cancer .

Specifications

Chemical Name or Material Gefitinib
CAS 184475-35-2
Color White
Purity Grade Notes Research
Molecular Formula C22H24ClFN4O3
Quantity 500 mg
Synonym ZD1839
Solubility Information DMSO : 125 mg/mL (279.70 mM; Need ultrasonic)
SMILES ClC1=C(C=CC(NC2=NC=NC3=C2C=C(C(OC)=C3)OCCCN4CCOCC4)=C1)F
Molecular Weight (g/mol) 446.9
Formula Weight 446.9
Percent Purity 95.0%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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