Gefitinib, MedChemExpress

Product Code.	Quantity	Unit Size
16491926	500 mg	500mg
16487886	100 mg	100mg
16431949	1 g	1g
16480588	5 g	5g

Product Code. 16491926 Supplier Medchem Express Supplier No. HY50895

Description

MedChemExpress Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy and cell apoptosis, which can be used for cancer related research, such as Lung cancer and breast cancer .

Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy and cell apoptosis, which can be used for cancer related research, such as Lung cancer and breast cancer .

Specifications

• Chemical Name or Material: Gefitinib
• CAS: 184475-35-2
• Color: White
• Purity Grade Notes: Research
• Molecular Formula: C₂₂H₂₄ClFN₄O₃
• Quantity: 500 mg
• Synonym: ZD1839
• Solubility Information: DMSO : 125 mg/mL (279.70 mM; Need ultrasonic)
• SMILES: ClC1=C(C=CC(NC2=NC=NC3=C2C=C(C(OC)=C3)OCCCN4CCOCC4)=C1)F
• Molecular Weight (g/mol): 446.9
• Formula Weight: 446.9
• Percent Purity: 95.0%
• Grade: Research
• Physical Form: Powder
• For Use With (Application): Cancer-Kinase/protease

Research purposes only