GE Healthcare Sepharose™ Fast Flow Cation Exchange Media

Used for preparative protein separations in both research and industrial applications. GE Healthcare CM Sepharose™ Fast Flow Cation Exchange Media is composed of crosslinked 6% agarose beads, with carboxymethyl (CM) weak cation exchange groups.

Overview
Brand: GE Healthcare

Manufacturer Part Number: 17-0719-10

UNSPSC: 41115700

Code: GE

Additional Details:
Additional Details: Weight: 0.11000kg



Product Code. 10059859

Quantity Price
1 £ 52.44 / 25mL
Estimated Shipment
23-05-2017
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Description and Specification

Specification

Binding Capacity 50mg ribonuclease A/mL medium
Packaging Quantity 25mL
Particle Size 45 to 165μm
Product Type CM Sepharose Fast Flow
pH Range 4 to 13

  • Hydrophilic nature of base matrix ensures low levels of non-specific binding leading to low levels of host cell-derived impurities in the elution pool
  • Composed of crosslinked 6% agarose beads
  • Reproducible
  • Part of Sepharose Fast Flow ion exchange platform
  • High chemical stability, allowing well proven cleaning-in-place (CIP) and sanitization protocols
  • Available in range of pre-packed process development tools

SP Sepharose:

  • Ligand: Sulphopropyl
  • Ion Exchanger Type: Strong cation exchanger
  • Ionic Capacity: 0.18 to 0.25mmol H+/mL medium
  • Binding capacity: 70mg ribonuclease A/mL medium
CM Sepharose:
  • Ligand: Carboxymethyl
  • Ion Exchanger Type: Weak cation exchanger
  • Ionic Capacity: 0.09 to 0.13mmol Hl+/mL medium
  • Binding capacity: 50mg ribonuclease A/mL medium

Used extensively for capture and intermediate purification of wide range of approved biopharmaceuticals