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GE Healthcare HiTrap™ MabSelect™ Prepacked Columns

Use these columns in small-scale MAb purification in a continuous bioprocess. GE Healthcare Life Sciences™ HiTrap™ MabSelect™ Prepacked Columns for fast purification of monoclonal antibodies (Mabs) from large sample volumes

Brand:  GE Healthcare 28-4082-53

Code : GE

Additional Details : Weight : 2.01390kg


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Product Code. 10359534

  • £629.43 / Pack of 5


Estimated Shipment
19-12-2017
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If this item is out of stock, delivery will be in 3-4 working days providing the item is in stock at the supplier.
Please enquire with customer services on 01509 555500 for stock availability.

 

Description

Description

Prepacked HiTrap columns for process development, screening of purification conditions, and small-scale purification of Mabs. MabSelect media are suited for the high flowrates and pressures required when scaling up.

  • Oriented coupling of recombinant Protein A ligand to the agarose matrix via an engineered C-terminal cysteine increases IgG binding capacity over other protein A media
  • High capacity, low ligand leakage, and high-flow base matrix allow purification of Mabs at process scale
  • Fewer regulatory concerns due to the total absence of mammalian culture in the ligand production and purification
  • Designed for use with a syringe, a peristaltic pump, or a chromatography system

MabSelect

  • Allows at least five times higher flowrates than conventional cross-linked agarose of similar porosity
  • Recombinant Protein A ligand promotes specificity of binding to Fc region of IgG; permits one-step purification
MabSelect Xtra™
  • Same recombinant protein A ligand as MabSelect, but with a smaller particle size and greater porosity, for increased dynamic binding capacity
  • Allows binding from samples with high expression levels of the monoclonal antibody
  • Lowers overall production cost due to the possibility of processing concentrated feedstocks in fewer batches
MabSelect SuRe™ (Superior Resistance)
  • Akali-tolerant protein A-derived ligand allows the use of up to 0.5M NaOH for cleaning-in-place (CIP)
  • Permits significant cost savings and extension of cycles in regular production

Specifications

Specifications

0.7cm
1mL
4° to 30°C
≈30mg Human lgG/mL at 2.4 min. residence time
5 Pack
For fast purification of monoclonal antibodies from large sample volumes, Protein Purification
20% Ethanol
1mL
<4mL/min.
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Safety and Handling

Safety and Handling

Product Identifier
  • HiTrap MabSelect, 1 ml, 5 x 1 ml

Signal Word
  • Warning

Hazard Category
  • Flammable liquid Category 3

Hazard Statement
  • H226-Flammable liquid and vapour.

Precautionary Statement
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • P241-Use explosion-proof electrical/ventilating/lighting/A§/ equipment.
  • P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
  • P235-Keep cool.
  • P501-Dispose of contents/container to A§.

Supplemental information
  • MIXTURE LIST-Contains : ethanol