GE Healthcare HiScreen™ MabSelect™, Xtra™, SuRe™, SuRe LX™ Prepacked Columns

Designed for method optimization and parameter screening for capture of monoclonal antibodies.   GE Healthcare HiScreen™ MabSelect™, Xtra™, SuRe™, SuRe LX™ Prepacked Columns come ready-to-use  for convenience.

Overview
Brand: GE Healthcare

Manufacturer Part Number: 17-5474-15

X1 PREPACKED COLUMN, HISCREEN(TM) MABSELECT(TM) SURE, 4.7ML Volume

UNSPSC: 41116104

Code: GX

Additional Details:
Additional Details: Weight: 0.08500kg



Product Code. 11603084

Quantity Price
1 £ 762.94 / Each
Estimated Shipment
23-12-2016
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Description and Specification

Specification

Buffer 8M Urea, 6M Guanidine Hydrochloride, 2% Benzyl Alcohol or 20% Ethanol
Column Type HiScreen MabSelect SuRe LX Prepacked Column
Format Column
Includes Stoppers at the inlet and outlet
Kit Size 1 x 4.7mL
Bed Support Filter
Binding Capacity ≈60mg Human IgG
Diameter (Metric) Inner 0.77cm
Product Type HiScreen MabSelect SuRe LX Prepacked Column
Height (Metric) Bed 10cm
For Use With (Application) Designed for method optimization and parameter screening for capture of monoclonal antibodies
Ligand Alkali-stabilized Protein A-derived (E. coli)
Ligand Coupling Method Epoxy Activation
Material Polypropylene
Particle Size 85μm
Max. Pressure 3bar
pH 3 to 12
Storage Requirements 2° to 8°C

  • Ready-to-use columns for convenient process development
  • Rigid, highly cross-linked agarose matrix
  • Bed height of 10cm is designed to allow method optimization and parameter screening
  • Easily connected in series to achieve 20cm bed height
  • Small bed volume (4.7mL) gives fast result and minimal sample/buffer consumption
  • Reproducible results, scalable to BioProcess columns packed with the same chromatography media using the same linear fluid velocity

MabSelect

  • For capture of MAbs from large sample volumes
  • Prepacked with protein A-derived media
  • Compatible with high flow rates and high pressure when scaling up
MabSelect Xtra
  • Increased binding capacity enables purification of MAbs from high-level expression feedstock
  • Also optimized for Fc-fusion proteins
  • Very low, unspecific binding due to high ligand selectivity and matrix hydrophilicity
  • Prepacked with protein A-derived media
MabSelect SuRe (Superior Resistance) and MabSelect SuRe (Superior Resistance) LX
  • With novel, alkali-tolerant recombinant protein A ligand that provides greater stability and allows use of 0.1 to 0.5M sodium hydroxide for cleaning-in-place (CIP)
  • Enhanced protease resistance resulting in lower ligand leakage
  • High dynamic binding capacity