GDC-0834, MedChemExpress

MedChemExpress GDC-0834 is a potent and selective BTK inhibitor. GDC-0834 inhibits BTK with an in vitro IC50 of 5.9 and 6.4 nM in biochemical and cellular assays, respectively, and in vivo IC50 of 1.1 and 5.6 μM in mouse and rat, respectively.

Product Code	Brand	Quantity
16486508	Medchem Express HY-15427	10 mg
16462607	Medchem Express HY-15427	50 mg
16419097	Medchem Express HY-15427	5 mg

Description

GDC-0834 is a potent and selective BTK inhibitor. GDC-0834 inhibits BTK with an in vitro IC50 of 5.9 and 6.4 nM in biochemical and cellular assays, respectively, and in vivo IC50 of 1.1 and 5.6 μM in mouse and rat, respectively.

Specifications

• Chemical Name or Material: GDC-0834
• CAS: 1133432-49-1
• Purity Grade Notes: Research
• For Use With (Application): COVID-19-immunoregulation
• SMILES: O=C(C1=CC(CCCC2)=C2S1)NC3=CC=CC(C(N=C4NC5=CC=C([C@H]6N(C)CCN(C)C6=O)C=C5)=CN(C)C4=O)=C3C
• Formula Weight: 596.74
• Grade: Research

• Physical Form: Solid
• Color: Light Yellow
• Molecular Formula: C₃₃H₃₆N₆O₃S
• Solubility Information: DMSO : ≥ 32 mg/mL (53.62 mM)
• Molecular Weight (g/mol): 596.74
• Percent Purity: 98.21%

Safety and Handling

missing translation for 'shelfLife' : Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month

Recommended Storage : Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month

Research purposes only