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GDC-0834, MedChemExpress

Product Code. 16486508
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Product Code. 16486508 Supplier Medchem Express Supplier No. HY15427

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Description

MedChemExpress GDC-0834 is a potent and selective BTK inhibitor. GDC-0834 inhibits BTK with an in vitro IC50 of 5.9 and 6.4 nM in biochemical and cellular assays, respectively, and in vivo IC50 of 1.1 and 5.6 μM in mouse and rat, respectively.

GDC-0834 is a potent and selective BTK inhibitor. GDC-0834 inhibits BTK with an in vitro IC50 of 5.9 and 6.4 nM in biochemical and cellular assays, respectively, and in vivo IC50 of 1.1 and 5.6 μM in mouse and rat, respectively.

Specifications

Chemical Name or Material GDC-0834
Physical Form Solid
CAS 1133432-49-1
Color Light Yellow
Quantity 10 mg
Purity Grade Notes Research
Molecular Formula C33H36N6O3S
For Use With (Application) COVID-19-immunoregulation
Solubility Information DMSO : ≥ 32 mg/mL (53.62 mM)
SMILES O=C(C1=CC(CCCC2)=C2S1)NC3=CC=CC(C(N=C4NC5=CC=C([C@H]6N(C)CCN(C)C6=O)C=C5)=CN(C)C4=O)=C3C
Molecular Weight (g/mol) 596.74
Formula Weight 596.74
Percent Purity 98.21%
Grade Research
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Research purposes only

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