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Invitrogen™ GCP5 Polyclonal Antibody
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Product Code. 17218873 Shop All Thermo Scientific Products
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Quantity:
100 μL
Unit Size:
100µL
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17218873 100 μL 100µL
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Product Code. 17218873 Supplier Invitrogen™ Supplier No. PA5116089

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total TUBGCP5.

The gamma-Tubulin complex is composed of gamma Tubulin and the gamma-Tubulin complex associated proteins GCP2, GCP3, GCP4, GCP5 and GCP6, all of which are essential components of microtubule organizing centers. gamma-Tubulin complex components are localized to both the centrosome, where they are involved in microtubule nucleation, and to the cytoplasm, where they exist as soluble complexes that can be recruited to the centrosome as needed. Although the GCP proteins are related, they have distinct roles which contribute to the proper function of the gamma-Tubulin complex. GCP5 ( gamma-Tubulin complex component 5), also known as TUBGCP5, is a 1, 024 amino acid member of the gamma-Tubulin complex and is highly expressed in heart and skeletal muscle. Defects in the gene encoding GCP5 are implicated in Prader-Willi syndrome (PWS), a rare genetic disorder associated with obesity, compulsive behavior and lower intellectual ability.
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Specifications

Antigen GCP5
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene Tubgcp5
Gene Accession No. Q8BKN5, Q96RT8
Gene Alias B130010C12Rik; Gamma-tubulin complex component 5; gamma-tubulin complex component GCP5; GCP5; GCP-5; KIAA1899; mKIAA1899; Tubgcp5; tubulin gamma complex associated protein 5; tubulin, gamma complex associated protein 5
Gene Symbols Tubgcp5
Host Species Rabbit
Immunogen A synthesized peptide derived from human TUBGCP5(Accession Q96RT8), corresponding to amino acid residues Y512-A562.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114791, 233276, 308663
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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