Invitrogen™ GCP4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA575415

Product Code. 15911945

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

The gamma-Tubulin complex is composed of gamma Tubulin and the gamma-Tubulin complexassociated proteins GCP2, GCP3, GCP4, GCP5 and GCP6, all of which are essential components of microtubule organizing centers. gamma-Tubulin complex components are localized to both the centrosome, where they are involved in microtubule nucleation, and to the cytoplasm, where they exist as soluble complexes that can be recruited to the centrosome as needed. Although the GCP proteins are related, they have distinct roles which contribute to the proper function of the gamma-Tubulin complex. GCP4 (gamma-Tubulin complex component 4), also known as TUBGCP4, is a ubiquitously expressed 667 amino acid member of the gamma-Tubulin complex that localizes to the metaphase spindle during mitosis. In response to proteosome inhibition, GCP4 exhibits increased accumulation at the pericentiolar material where it participates in microtubule organization and nucleation.

Specifications

• Antigen: GCP4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TUBGCP4
• Gene Alias: 4932441P04Rik; 76P; D2Ertd435e; gamma tubulin ring complex protein; gamma tubulin ring complex protein (76p gene); gamma-ring complex protein 76 kDa; Gamma-tubulin complex component 4; GCP4; GCP-4; Grip76; h76p; hGCP4; hGrip76; MCCRP3; RGD1306924; TUBGCP4; tubulin gamma complex associated protein 4; tubulin, gamma complex associated protein 4
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 27229, 362203, 51885
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% sodium azide; pH 7.2
• Gene Accession No.: Q9D4F8, Q9UGJ1
• Gene Symbols: TUBGCP4
• Immunogen: Synthetic peptide corresponding to amino acids 197-243 of Human GCP4.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG