Invitrogen™ GCN4 Chimeric Recombinant Mouse Monoclonal Antibody (C11L34)

Mouse Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA547957

Product Code. 17961151

Description

Specificity: This antibody binds to the HLENEVARLKK peptide from the leucine-zipper domain of the S. cerevisiae GCN4 transcriptional activator with picomolar affinity.

GCN4 is a transcription factor protein in yeast that plays a crucial role in the regulation of genes involved in amino acid biosynthesis, such as HIS4, HIS7, HIS3, ARG1, ARG3, ARG4, and ARG5,6. The protein contains a basic leucine zipper (bZIP) domain that enables it to bind to specific DNA sequences, thereby regulating the transcription of target genes. The protein is also involved in the regulation of other cellular processes, including stress response and nutrient signaling, such as GSH1, YAP1, and TRX2. Its structure is composed of a dimeric coiled-coil domain, which allows for protein-protein interactions, and a DNA-binding bZIP domain.

Specifications

• Antigen: GCN4 Chimeric
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% ProClin 300
• Gene Accession No.: P03069
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 856709
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Immunoprecipitation, Western Blot, Immunocytochemistry, Surface Plasmon Resonance
• Clone: C11L34
• Conjugate: Unconjugated
• Gene: GCN4
• Gene Symbols: GCN4
• Immunogen: Biotinylated GCN4-peptide (HLENEVARLKK).
• Quantity: 200 μg
• Primary or Secondary: Primary
• Target Species: Yeast
• Product Type: Antibody
• Isotype: IgG1 λ