Invitrogen™ GCM2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA522157

Product Code. 13219598

Description

Recommended positive controls: A431. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene is a homolog of the Drosophila glial cells missing gene, which is thought to act as a binary switch between neuronal and glial cell determination. The protein encoded by this gene contains a conserved N-terminal GCM motif that has DNA-binding activity. The protein is a transcription factor that acts as a master regulator of parathyroid development. It has been suggested that this transcription factor might mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells. Mutations in this gene are associated with hypoparathyroidism.

Specifications

• Antigen: GCM2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GCM2
• Gene Alias: chorion-specific transcription factor GCMb; GCM motif protein 2; Gcm1; Gcm1-rs2; GCM2; Gcm-2; Gcmb; gcmB transcription factor; Gcm-rs1; glial cell missing-like protein; glial cells missing 2; glial cells missing homolog 2; glial cells missing homolog 2 (Drosophila); glial cells missing homolog b; glial cells missing transcription factor 2; glial cells missing-like protein 2; glide/gcm protein homolog; hGCMb; mero; merovingian; mGCMb; RP3-417M14.3; transcription factor glial cells missing-2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9247
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.75 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O75603
• Gene Symbols: GCM2
• Immunogen: Recombinant protein encompassing a sequence within the center region of human GCM2. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG