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Invitrogen™ GCKR Polyclonal Antibody

Description
Recommended positive controls: mouse liver. Predicted reactivity: Mouse (92%), Rat (92%), Dog (96%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).
Specifications
Specifications
| Antigen | GCKR |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7 |
| Gene | Gckr |
| Gene Accession No. | Q14397, Q91X44 |
| Gene Alias | FGQTL5; Gckr; GKRP; GLRE; glucokinase (hexokinase 4) regulator; glucokinase regulator; Glucokinase regulatory protein; hexokinase 4 |
| Gene Symbols | Gckr |
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