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GCK Rabbit anti-Mouse, Rat, Polyclonal, Proteintech

Product Code. 16869134 Shop All Proteintech Products
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150 μL
Unit Size:
150µL
20µL
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16869134 150 μL 150µL
16879134 20 μL 20µL
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Product Code. 16869134 Supplier Proteintech Supplier No. 196661AP150UL

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Description

Rabbit Polyclonal Antibody

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI).

Specifications

Antigen GCK
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.17 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Gck
Gene Accession No. P17712, P52792
Gene Alias GCK, GK, GLK, Glucokinase, glucokinase (hexokinase 4), Hexokinase 4, Hexokinase D, Hexokinase type IV, HHF3, HK IV, HK4, HKIV, HXKP, MODY2
Gene Symbols Gck
Host Species Rabbit
Immunogen GCK Fusion Protein Ag8116
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 103988, 24385
Target Species Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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