GCK Rabbit anti-Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16879134	Proteintech 19666-1-AP-20UL	20 μL
16869134	Proteintech 19666-1-AP-150UL	150 μL

Description

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI).

Specifications

• Antigen: GCK
• Applications: Immunoprecipitation, Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Rat, Mouse
• Gene Accession No.: P17712, P52792
• Gene ID (Entrez): 103988, 24385
• Immunogen: GCK Fusion Protein Ag8116
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: Gck

• Concentration: 0.17 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: GCK, GK, GLK, Glucokinase, glucokinase (hexokinase 4), Hexokinase 4, Hexokinase D, Hexokinase type IV, HHF3, HK IV, HK4, HKIV, HXKP, MODY2
• Gene Symbols: Gck
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody