Invitrogen™ GBP5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA534541

Product Code. 15395461

Description

A suggested positive control is rat liver tissue lysate. PA5-34541 can be used with blocking peptide PEP-1584.

The guanylate-binding proteins (GBPs) are a family of interferon-induced GTP-binding proteins function in innate immunity against microbial and viral pathogens. In humans, there are seven GBPs from hGBP1 to hGBP7. Human GBP1 and GBP2 have been shown to exhibit antiviral activity as well as being able to regulate the inhibition of proliferation and invasion of endothelial cells in response to interferon (IFN). GBP5 promotes selective NALP3 inflammasome responses to pathogenic bacteria and soluble but not crystalline inflammasome priming agents.

Specifications

• Antigen: GBP5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GBP5
• Gene Alias: 5330409J06Rik; GBP5; GBP-5; Gbp5a; GBP-TA antigen; GTP-binding protein 5; Guanine nucleotide-binding protein 5; guanylate binding protein 5; guanylate nucleotide binding protein 5; guanylate-binding protein 5; muGBP-5; UNQ2427/PRO4987
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 115362, 229898, 362050
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q8CFB4, Q96PP8
• Gene Symbols: GBP5
• Immunogen: A 16 amino acid peptide near the carboxy terminus of human GBP5.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG